منابع مشابه
Self-splicing and trans-splicing ribozymes
The Journal of Clinical Investigation | August 2003 | Volume 112 | Number 3 The splicing activity of Group I and Group II introns can be harnessed as a molecular tool that may potentially revise any gene of interest. Although hurdles remain, progress has been made in the development of these ribozymes for therapeutic application. While gene therapy is showing promise in the treatment of some di...
متن کاملSelf-cloning in Streptomyces griseus of an str gene cluster for streptomycin biosynthesis and streptomycin resistance.
An str gene cluster containing at least four genes (strR, strA, strB, and strC) involved in streptomycin biosynthesis or streptomycin resistance or both was self-cloned in Streptomyces griseus by using plasmid pOA154. The strA gene was verified to encode streptomycin 6-phosphotransferase, a streptomycin resistance factor in S. griseus, by examining the gene product expressed in Escherichia coli...
متن کاملOptimized preparation and evaluation of 99mTc-Streptomycin
Introduction: The endemic occurrence of new strains of tuberculosis around the globe has initiated new research on developing diagnostic radiopharmaceutical based on antibiotics. Methods:Tc-99m labeled streptomycin was prepared using freshly milked 99mTcO4- and various concentrations of streptomycin, stannous chloride at various temperatures in high yield radio...
متن کاملStreptomycin
ever, certain adjuvants, e.g. para-aminosalicylic acid, may delay the development of drug-resistance. Streptomycin is not absorbed from the alimentary tract and, therefore, it must always be given intramuscularly as well as directly, where possible, into the spaces which it is desired to render free from bacteria. The drug is excreted by the kidney. After intramuscular injection an adequate blo...
متن کاملStreptomycin
THIS book is a practical guide wlhiclh deals with imiost of the cond(litionis which come wvithin the scope of plastic surgery as practised in the British Isles. The first six chapters arc devoted to basic principles such as the' use of free skin grafts, flaps and tube pedicles, transplantation of tissues othelthan skini and the treatment of wounds, burns, frostbite, scars and(i keloids. The nex...
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ژورنال
عنوان ژورنال: Nature
سال: 1990
ISSN: 0028-0836,1476-4687
DOI: 10.1038/346801a0